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NMR-based metabolomics in pediatric drug resistant epilepsy – preliminary results

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Epilepsy in children is the mostfrequent, heterogeneous and difcultto classify chronic neurologic condition with the etiology found in 35–40% of patients.Our aim is to detectthe metabolic diferences between the epileptic children and the children with no neurological abnormalities in orderto defne the metabolic background fortherapy monitoring.The studied group included 28 epilepsy patients (median age 12 months) examined with a diagnostic protocol including EEG, videoEEG, 24-hour-EEG,tests for inborn errors of metabolism, chromosomal analysis and molecular study.

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15035
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Publication Date: 
21/10/2019