Major subpopulations of Plasmodium falciparum in sub-Saharan Africa
Submitted by susan on Mon, 2019-09-09 11:46
Understanding genomic variation and population structure of Plasmodium falciparum across Africa is necessary to sustain progress toward malaria elimination. Genome clustering of 2263 P. falciparum isolates from 24 malaria-endemic settings in 15 African countries identified major western, central, and eastern ancestries, plus a highly divergent Ethiopian population. Ancestry aligned to these regional blocs, overlapping with both the parasite’s origin and with historical human migration.
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Publication Date:
23/08/2019