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Low dose effect of chronic lead exposure on neuromotor response impairment in children is moderated by genetic polymorphisms

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Previous research on children of the Cincinnati Lead Program Project (CCLP) showed a strong correlation of blood lead level with postural balance impairment. Here we investigated whether this association is dependent on genetic polymorphisms that are implicated with lead metabolism and/or neuromotor disorders, suggesting the role of gene-environment interaction in neurotoxicity of lead exposure in early life of children.

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http://www.krepublishers.com/02-Journals/JHE/JHE-23-0-000-000-2008-Web/JHE-23-3-000-000-2008-Abst-PDF/JHE-23-3-183-08-1800-Chakraborty-B-M/JHE-23-3-183-08-1800-Chakraborty-B-M-Tt.pdf
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Publication Date: 
01/03/2008