Feature Article

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Curcumin promotes A-beta fibrillation and reduces neurotoxicity in transgenic drosophila

The pathology of Alzheimer's disease (AD) is characterized by the presence of extracellular deposits of misfolded and aggregated amyloid-β (Aβ) peptide and intraneuronal accumulation of tangles comprised of hyperphosphorylated Tau protein. For several years, the natural compound curcumin has been proposed to be a candidate for enhanced clearance of toxic Aβ amyloid. In this study we have studied the potency of feeding curcumin as a drug candidate to alleviate Aβ toxicity in transgenic Drosophila.

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Publication Date: 
01/02/2012
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Food insecurity and glycemic control among low-income patients with type 2 diabetes

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233-238
Publication Date: 
01/02/2012

Food insecurity refers to the inability to afford enough food for an active, healthy life. Numerous studies have shown associations between food insecurity and adverse health outcomes among children. Studies of the health effects of food insecurity among adults are more limited and generally focus on the association between food insecurity and self-reported disease. We therefore examined the association between food insecurity and clinical evidence of diet-sensitive chronic disease, including hypertension, hyperlipidemia, and diabetes.

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Study of noise pollution during Deepawali festival in Kolhapur city of Maharashtra, India

Kolhapur city is a district place in the state of Maharashtra with population of 4,93,167. It is one of the emerging industrial and commercial city of Western Maharashtra. Problems of pollution along with noise pollution are increasing with time especially during the festival period. In the present study, continuous monitoring of noise levels was carried out during the three festive days of Deepawali in the month of November, 2009 at ten different sites within the Kolhapur city.

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01/02/2012
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susan's picture

Least-cost network evaluation of centralized and decentralized contributions to global electrification

The choice between centralized and decentralized electricity generation is examined for 150 countries as a function of population distribution, electricity consumption, transmission cost, and the cost difference between decentralized and centralized electricity generation. A network algorithm is developed to find the shortest centralized transmission network that spans a given fraction of the population in a country. The least-cost combination of centralized and decentralized electricity that serves the country is determined.

286–302
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01/02/2012
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Preparing for smart grid technologies: A behavioral decision research approach to understanding consumer expectations about smart meters

With the enactment of the 2009 American Recovery and Reinvestment Act, U.S. President Obama made a public commitment to a new approach to energy production and transmission in the United States. It features installing smart meters and related technologies in residential homes, as part of transforming the current electrical grid into a “smart grid.” Realizing this transformation requires consumers to accept these new technologies and take advantage of the opportunities that they create.

790–797
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01/02/2012
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susan's picture

Union budget 2012 and its impact on wind energy sector

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Renewable energy is a sunrise industry, offering huge potential for employment generation, besides promising energy security for a developing country like India. However, the Union Budget 2012 has failed to provide for it the much needed impetus.

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01/02/2012
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Global monthly water scarcity: Blue water footprints versus blue water availability

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1-9
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01/02/2012

Freshwater scarcity is a growing concern, placing considerable importance on the accuracy of indicators used to characterize and map water scarcity worldwide. We improve upon past efforts by using estimates of blue water footprints (consumptive use of ground- and surface water flows) rather than water withdrawals, accounting for the flows needed to sustain critical ecological functions and by considering monthly rather than annual values. We analyzed 405 river basins for the period 1996–2005.

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A decisive month

Germany is outraged at major cuts for solar electricity and at the possibility of cuts to other renewables being snuck in through the back door.

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01/02/2012
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Fragile base

To protect the climate and overhaul our energy supply, we will need to do more than just expand renewables, we will need to do more than just expand renewables - we also have to start using energy more efficiently. But planned EU regulations are meeting with fierce resistance.

12-14
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01/02/2012
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Bird hunting in Mishmi hills of Arunachal Pradesh, north-eastern India

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Arunachal Pradesh is rich in biodiversity and has become a hub of scientific explorations leading to the discovery of new taxa species. Of late Arunachal Pradesh has become the focus of national and international wildlife research and conservation, partly due to its status of being in the Eastern Himalayas 'biodiversity hotspot'.

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