Feature Article

The objective of the study was to investigate the impact of introducing a rapid test as the first-line diagnostic test for drug-sensitive tuberculosis in Cape Town, South Africa.

Original Source

India was estimated to have the largest numbers of stillbirths globally in 2015, and the Indian government has adopted a target of <10 stillbirths per 1,000 births by 2030 through the India Newborn Action Plan (INAP). The objective of this study was to use verbal autopsy interviews to examine factors associated with stillbirth in the Indian state of Bihar and make recommendations for the INAP to better inform the setting of priorities and actions to reduce stillbirths.

Giant radio galaxies (GRGs) are one of the largest astrophysical sources in the Universe with an overall projected linear size of ∼0.7 Mpc or more. The last six decades of radio astronomy research has led to the detection of thousands of radio galaxies. However, only ∼300 of them can be classified as GRGs. The reasons behind their large size and rarity are unknown. We carried out a systematic search for these radio giants and found a large sample of GRGs.

Suicide is a stark indicator of human hardship, yet the causes of these deaths remain understudied, particularly in developing countries. This analysis of India, where one fifth of the world’s suicides occur, demonstrates that the climate, particularly temperature, has strong influence over a growing suicide epidemic. With 47 y of suicide records and climate data, I show that high temperatures increase suicide rates, but only during India’s growing season, when heat also reduces crop yields. My results are consistent with widely cited theories of economic suicide in India.

Predicting the impact of climate change and human activities on river systems is imperative for effective management of aquatic ecosystems. Unique information can be derived that is critical to the survival of aquatic species under dynamic environmental conditions. Therefore, the response of a tropical river system under climate and land-use changes from the aspects of water temperature and dissolved oxygen concentration were evaluated.

A number of new crops have been developed that address important traits of particular relevance for smallholder farmers in Africa. Scientists, policy makers, and other stakeholders have raised concerns that the approval process for these new crops causes delays that are often scientifically unjustified. This article develops a real option model for the optimal regulation of a risky technology that enhances economic welfare and reduces malnutrition. We consider gradual adoption of the technology and show that delaying approval reduces uncertainty about perceived risks of the technology.

This paper aims to extend and update the survey of extreme wave events in Ireland that was previously carried out by O'Brien et al. (2013). The original catalogue highlighted the frequency of such events dating back as far as the turn of the last ice age through to 2012. Ireland's marine territory extends far beyond its coastline and is one of the largest seabed territories in Europe. It is therefore not surprising that extreme waves have continued to occur regularly since 2012, particularly considering the severity of weather during the winters of 2013–14 and 2015–16.

Designing biologically inspired nanoscale molecular assembly with desired functionality is a challenging endeavour. Here we report the designing of fbrin-inspired nanostructured peptide based sealants which facilitate remarkably fast entrapping of blood corpuscles (~28 seconds) in contrast to fbrin (~56 seconds). Our engineered sealants are stabilized by lysine-aspartate ionic interactions and also by Nε (γ-glutamyl) lysine isopeptide bond mediated covalent interaction.

Northern Thailand has been experiencing the impact of climate change due to its fragile agro-ecosystem, inhabited by a resource-poor population. The study, conducted in a mountainous landscape of Doi Mae Salong area in Northern Thailand, explores the farmers’ perceptions of climate change, its impact on farming, and adaptation measures undertaken by the two ethnic communities in the area for coping with climate change impacts. The data were collected through a structured questionnaire survey of ninety farm households using the recall approach for the past twenty years.

A significant reduction in summer monsoon rainfall has been observed in northern central India during the second half of the twentieth century, threatening water security and causing widespread socio-economic impacts. Here, using various observational data sets, we show that monsoon rainfall has increased in India at 1.34 mm d−1 decade−1 since 2002. This apparent revival of summer monsoon precipitation is closely associated with a favourable land–ocean temperature gradient, driven by a strong warming signature over the Indian subcontinent and slower rates of warming over the Indian Ocean.